PD1 antibody [NAT105]

Catalogue Number: GTX20256-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:programmed cell death 1 , CD279 , PD-1 , PD1 , SLEB2 , hPD-1 , hPD-l , hSLE1
Shipping Condition:Blue Ice
Unit(s): 500 ul
Host name: Mouse
Clone: NAT105
Isotype: IgG1
Immunogen:
Application: FACS, ICC, IF, IHC-P, IP, WB, IHC-Fr, IHC

Description

Description: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

PDCD1

Gene ID

5133

Molecular Weight

32

Uniprot ID

Q15116

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-P: 1:25-100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.