FAK (phospho Tyr397) antibody
Catalogue Number: GTX24803-GTX
GTX24803 Image
GTX24803 Image
GTX24803 Image
WB analysis of samples using GTX24803 FAK (phospho Tyr397) antibody prior incubated with the non-phosphopeptide corresponding to the phosphopeptide immunogen (Lane 2), a generic phosphotyrosine containing peptide(Lane 3), the phosphopeptide corresponding to FAK (phospho Tyr402) , or the phosphopeptide immunogen (Lane 5). The data show that only the immunogen phosphopeptide blocks the signal, demonstrating the specificity of the antibody.
GTX24803 Image
ICC/IF analysis of HeLa cells using GTX24803 FAK (phospho Tyr397) antibody. Green : Primary antibody Blue : cell nucleus Fixation/Permeabilization : ice-cold 95% methanol
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Liquid |
| Type: | ChIP Validated Antibodies |
| Alias: | protein tyrosine kinase 2 , FADK , FAK , FAK1 , FRNK , PPP1R71 , p125FAK , pp125FAK |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human FAK that contains tyrosine 397. The sequence is conserved in mouse, rat, chicken and frog. |
| Application: | ICC, IF, IP, ChIP, WB, IHC-Fr |
Description
Description: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Additional Text
Gene Name
PTK2
Gene ID
5747
Uniprot ID
Q05397
Purification
Affinity Purified
Modification
Phosphorylated, Tyr397
Molecular Weight
119
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
GTX24803 Datasheet
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