Cytokeratin 8 antibody [SPM538]

Catalogue Number: GTX34665-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CARD2 , CK8 , CYK8 , K2C8 , K8 , KO , KRT8 , keratin 8 , Cytokeratin 8 , Keratin 8
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: SPM538
Isotype: IgG1
Immunogen: Cytoskeleton preparation containing cytokeratin 8
Application: FACS, ICC, IF, IHC-P

Description

Description: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Additional Text

Gene Name

KRT8

Gene ID

3856

Uniprot ID

P05787

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Molecular Weight

54

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ICC/IF: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 min at RT. FACS: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.