TIMP2 antibody [3A4]
Catalogue Number: GTX35122-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CSC21K , DDC8 , TIMP metallopeptidase inhibitor 2 , TIMP2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 3A4 |
| Isotype: | IgG2a |
| Immunogen: | A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI) |
| Application: | FACS, ICC, IF, IHC-P, WB |
Description
Description: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
Additional Text
Uniprot ID
P16035
Gene Name
TIMP2
Gene ID
7077
Molecular Weight
24
Purification
Protein A/G Purified
Concentration
0.2 mg/ml
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1-2µg/ml. ICC/IF: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. FACS: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX35122 Datasheet
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