TNF alpha antibody [P/T2]

Catalogue Number: GTX35133-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	DIF , TNF , TNFA , TNFSF2 , TNFalpha , TNLG1F , tumor necrosis factor , TNF alpha
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	P/T2
Isotype:	IgM
Immunogen:	A hexadecapeptide corresponding to aa115-130 (NGVELRDNQLVVPSEG) of human TNF- , conjugated to thyroglobulin
Application:	FACS, ICC, IF, IHC-P

Overview
Datasheets

Description

Description: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

TNF

Gene ID

7124

Uniprot ID

P01375

Concentration

0.2 mg/ml

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Application Notes

ICC/IF: 1-2µg/ml. IHC-P: 2-4µg/ml for 30 min at RT. FACS: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX35133 Datasheet

Price

£465.00

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Quantity
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