CD4 antibody [GK1.5]
Catalogue Number: GTX44531-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.09% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CD4 antigen , L3T4 , Ly-4 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | GK1.5 |
| Isotype: | IgG2b |
| Immunogen: | Murine CD4. |
| Application: | FACS, ICC, IF, IHC-P, IP, WB, IHC-Fr, NT, Inh, Depl |
Additional Text
Gene Name
CD4
Gene ID
12504
Concentration
0.5 mg/ml
Purification
Affinity Purified
Uniprot ID
P06332
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
51
Short Description
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such a
GTX44531 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations