PSMD10 antibody

Catalogue Number: GTX48519-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:proteasome 26S subunit, non-ATPase 10 , dJ889N15.2 , p28 , p28(GANK)
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide made to an internal portion of the human Gankyrin protein sequence (between residues 100-200). [UniProt# O75832]
Application: FACS, ICC, IF, WB

Description

Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20. [provided by RefSeq]

Additional Text

Gene Name

PSMD10

Molecular Weight

24

Gene ID

5716

Uniprot ID

O75832

Concentration

0.97 mg/ml

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 2 µg/ml. ICC/IF: 1:500. FACS: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.