SLC31A1 / CTR1 antibody

Catalogue Number: GTX48534-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:solute carrier family 31 member 1 , COPT1 , CTR1
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide derived from a C-terminal sequence of human SLC31A1/CTR1 [UniProt# O15431]
Application: ICC, IF, IHC-P, WB, IHC-Fr, IHC

Description

Description: Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM]

Additional Text

Concentration

1 mg/ml

Uniprot ID

O15431

Gene Name

SLC31A1

Purification

Affinity Purified

Gene ID

1317

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

21

Application Notes

ICC/IF: 1:500. IHC-P: 1:250. IHC: 1:250. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.