TIE1 antibody [12D9]

Catalogue Number: GTX52470-GTX

Manufacturer:GeneTex
Preservative:No preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:JTK14 , TIE , TIE1 , tyrosine kinase with immunoglobulin like and EGF like domains 1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 12D9
Isotype: IgG1
Immunogen: hTie1 extracellular domain
Application: IHC-P, WB

Description

Description: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Additional Text

Gene ID

7075

Gene Name

TIE1

Uniprot ID

P35590

Concentration

200 ug/ml

Purification

Protein G purified

Molecular Weight

125

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.