TIE2 antibody [21G7]

Catalogue Number: GTX52471-GTX

Manufacturer:GeneTex
Preservative:No preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD202B , TEK , TEK receptor tyrosine kinase , TIE2 , VMCM , VMCM1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 21G7
Isotype: IgG1
Immunogen: hTie2 extracellular domain
Application: ELISA, IHC-P, WB

Description

Description: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Additional Text

Uniprot ID

Q02763

Gene ID

7010

Gene Name

TEK

Concentration

200 ug/ml

Purification

Protein G purified

Molecular Weight

126

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:1000. ELISA: 1:1000 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.