CTLA4 antibody [IHC004]
Catalogue Number: GTX57204-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.09% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Cytotoxic T-Lymphocyte Associated Protein 4 , Alps5 , Cd , Cd152 , Celiac3 , Ctla-4 , Grd4 , Gse , Iddm12 , Ctla4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ul |
| Host name: | Mouse |
| Clone: | IHC004 |
| Isotype: | IgG1 |
| Immunogen: | Recombinant CTLA4 protein. |
| Application: | IHC-P |
Description
Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
1493
Gene Name
CTLA4
Purification
Protein A purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
25
Application Notes
IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX57204 Datasheet
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