Carbonic Anhydrase IX antibody [HL1410]

Catalogue Number: GTX636876-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:carbonic anhydrase 9 , CAIX , MN
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL1410
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Carbonic Anhydrase IX. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, WB

Description

Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014]

Additional Text

Gene ID

768

Concentration

1 mg/ml

Gene Name

CA9

Molecular Weight

50

Uniprot ID

Q16790

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Application Notes

WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.