beta Catenin antibody [HL1753]
Catalogue Number: GTX637403-GTX
| Manufacturer: | GeneTex |
| Preservative: | No Preservative |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | catenin beta 1 , CTNNB , EVR7 , MRD19 , armadillo |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | HL1753 |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human beta Catenin |
| Application: | ICC, IF, IHC-P, WB |
Description
Description: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Additional Text
Gene Name
CTNNB1
Concentration
1 mg/ml
Gene ID
1499
Uniprot ID
P35222
Molecular Weight
85
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Application Notes
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX637403 Datasheet
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