Catalogue Number: GTX637658-GTX
Manufacturer: | GeneTex |
Preservative: | No Preservative |
Physical state: | Liquid |
Type: | Recombinant Monoclonal |
Alias: | ataxin 3 , AT3 , ATX3 , JOS , MJD , MJD1 , SCA3 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 25 ul |
Host name: | Rabbit |
Clone: | HL1909 |
Isotype: | IgG |
Immunogen: | Recombinant fragment of human Ataxin 3. |
Application: | ICC, IF, IHC-P, WB |
Description: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016]
ATXN3
P54252
1 mg/ml
4287
Protein A purified
Recombinant Monoclonal
41
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.