GLP1R antibody [HL2297]
Catalogue Number: GTX638352-GTX
| Manufacturer: | GeneTex |
| Preservative: | No preservative |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | glucagon like peptide 1 receptor , GLP-1 , GLP-1-R , GLP-1R |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | HL2297 |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of human GLP1R. |
| Application: | WB |
Description
Description: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Additional Text
Gene ID
2740
Concentration
2 mg/ml
Gene Name
GLP1R
Uniprot ID
P43220
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Application Notes
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX638352 Datasheet
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