Fibrillarin antibody

Catalogue Number: GTX65859-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	fibrillarin , FIB , FLRN , Nop1 , RNU3IP1
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Recombinant funsion protein containing a sequence corresponding to amino acids 100-321 of human FBL (NP_001427.2).
Application:	ICC, IF, IHC-P, IP, WB

Overview
Datasheets

Description

Description: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

FBL

Uniprot ID

P22087

Purification

Affinity Purified

Gene ID

2091

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Application Notes

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. IP: 1:20 - 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX65859 Datasheet

Price

£329.00

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