Hec1 (phospho Ser 55) antibody
Catalogue Number: GTX70017-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.025% ProClin 300 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | NDC80 kinetochore complex component , HEC , HEC1 , HsHec1 , KNTC2 , TID3 , hsNDC80 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Carrier-protein conjugated synthetic peptide surrounding phospho Ser55 of human Hec1. The exact sequence is proprietary. |
| Application: | ELISA, ICC, IF, IP, WB |
Description
Description: HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM]
Additional Text
Gene ID
10403
Gene Name
NDC80
Uniprot ID
O14777
Concentration
0.26 mg/ml
Purification
Affinity Purified
Molecular Weight
80
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Modification
Phosphorylated, Ser55
Application Notes
Recommended Starting Dilutions:For WB: 1:500-1:3000For IP: Use at a dilution of 2-4 µg/mL for 1 mg cell extractFor ICC/IF: Use at a dilution of 1:300Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.
GTX70017 Datasheet
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