IL1 beta antibody

Catalogue Number: GTX74034-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:interleukin 1 beta , IL-1beta , Il-1b
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant murine IL1 beta
Application: ELISA, ICC, IF, IHC-P, WB, IHC-Fr

Additional Text

Uniprot ID

P10749

Gene Name

IL1B

Gene ID

16176

Purification

Affinity Purified

Concentration

1.79 mg/ml

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

31

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. ELISA: 0.5-2µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

Interleukin-1 beta (IL-1 beta) antibody detects IL-1 beta protein, which is a proinflammatory cytokine produced by active macrophages. In recent reports, IL-1 beta activation via caspase-1 can be induced by infectious pathogens in a process known as "pyroptosis", a form of programmed cell death that initiates an inflammatory antimicrobial response. IL-1 beta is also a key factor in cytokine storms associated with both infectious and non-infectious diseases.