Anti-CD3e (145-2C11) In Vivo Antibody - Ultra-Low Endotoxin
Catalogue Number: ICH1041UL-ICB
| Manufacturer: | IchorBio |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | T3/Leu-4 epsilon chain, CD3 epsilon chain, CD3e |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Armenian Hamster |
| Clone: | 145-2c11 |
| Isotype: | IgG |
| Immunogen: | H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37 |
| Application: | FC, IP, WB, IHC-Fr, Blk, InVivoCDepl |
Description
Description: CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Additional Text
Gene Name
CD3E
Purification
Protein A/G Purified
Gene ID
12501
Uniprot ID
P22646
Caution
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration
1-5 mg/ml
Antibody Clonality
Monoclonal
Application Notes
Blocking: The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells Each investigator should determine their own optimal working dilution for specific applications.
Storage Note
anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
ICH1041UL Datasheet
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