Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin
Catalogue Number: ICH1124-ICB
| Manufacturer: | IchorBio |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | IFN-b, IFN-beta, Type-1 interferon, Interferon beta |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Armenian Hamster |
| Clone: | MIB-5E9.1 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | WB, Blk |
Description
Description: Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-alpha proteins and a single IFN-beta protein. The second class, type II IFN, consists of a single protein, IFN-gamma. IFN-alpha and IFN-beta signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-beta has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-beta's therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
Additional Text
Concentration
1 mg/ml
Gene Name
IFNB1
Purification
Protein A/G Purified
UniProt ID
P01575
Gene ID
15977
Caution
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Antibody Clonality
Monoclonal
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Storage Note
anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
ICH1124 Datasheet
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