Catalogue Number: ICH1136UL-ICB
Manufacturer: | IchorBio |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
Host name: | Armenian Hamster |
Clone: | TN3-19.12 |
Isotype: | IgG |
Immunogen: | Recombinant mouse TNFalpha |
Application: | FC, IP, WB, FA, Blk |
Description: The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis. Clone TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha
P06804
TNF
21926
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Monoclonal
Each investigator should determine their own optimal working dilution for specific applications.
≥ 2 mg/ml
anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
This monoclonal antibody was purified using Protein A