Catalogue Number: ICH1191-ICB
Manufacturer: | IchorBio |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Endoglin, Ancillary TGF-beta Receptor |
Shipping Condition: | Blue Ice |
Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
Host name: | Rat |
Clone: | MJ7/18 |
Isotype: | IgG2a, kappa |
Immunogen: | MJ7/18 was produced by immunizing rats with inflamed mouse skin and selecting for reactivity with endothelial cells. MJ7/18 predominantly stains vascular endothelial cells and is a marker of mouse endothelium |
Application: | ELISA, FC, IF, IHC-P, IP, WB, IHC, Agon, Separation, LCImg |
Description: CD105 (endoglin) is a TGF-β superfamily co-receptor that promotes angiogenesis, is involved in endothelial integrin-mediated mural cell and leukocyte adhesion, antagonizes TGF-β mediated ERK activation, is essential to the immune response of macrophages, regulates trophoblast differentiation and invasion during pregnancy, promotes T-cell proliferation, and regulates differentiation and collagen expression in myofibroblasts
Protein A/G Purified
Monoclonal
Each investigator should determine their own optimal working dilution for specific applications.
≥ 2 mg/ml