Catalogue Number: ICH1202-ICB
Manufacturer: | IchorBio |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Ly-49 inhibitory receptors C |
Shipping Condition: | Blue Ice |
Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
Host name: | Mouse |
Clone: | 4LO3311 |
Isotype: | IgG3, kappa |
Immunogen: | 4LO3311 was generated by immunizing 129/SvJ mice with C57BL/6 NK-enriched spleen cells |
Application: | FC, IP, Depl |
Description: 4LO3311 recognizes an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain. 4LO3311 recognizes Ly-49CBALB but not Ly-49AB6, Ly-49ABALB, BBALB, DB6, EB6, FB6, GB6, GBALB, or H. 4LO3311 plus complement inhibits NK cell and antibody-dependent cellular cytotoxicity (ADCC) activity in C3H spleen cells4. 4LO3311 inhibits C57BL/6 and C3H NK cell activity but has no effect on NZB NK cells.
Protein A/G Purified
Monoclonal
Each investigator should determine their own optimal working dilution for specific applications.
≥ 2 mg/ml