Ado-Trastuzumab Emtansine Biosimilar - Research Grade
Catalogue Number: ICH4014-ICB
| Manufacturer: | IchorBio |
| Type: | Recombinant Monoclonal |
| Alias: | Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 mg, 5 mg |
| Host name: | |
| Clone: | |
| Isotype: | IgG1 |
| Immunogen: |
Description
Description: Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.
Additional Text
Gene ID
2064
Gene Name
ERBB2
Uniprot ID
P04626
Purification
Protein A/G Purified
Concentration
1-5 mg/ml
Antibody Clonality
Recombinant Monoclonal
Storage Note
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
ICH4014 Datasheet
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