Alirocumab Biosimilar - Research Grade

Catalogue Number: ICH4016-ICB

Manufacturer:	IchorBio
Type:	Recombinant Monoclonal
Alias:	Proprotein convertase subtilisin/kexin type 9, NARC-1, PC9
Shipping Condition:	Blue Ice
Unit(s):	10 mg, 20 mg, 5 mg, 50 mg, 1 mg, 100 mg
Host name:
Clone:
Isotype:	IgG1
Immunogen:

Overview
Datasheets

Description

Description: Alirocumab biosimilar is a human monoclonal antibody (IgG1 isotype) that targets proprotein convertase subtilisin kexin type 9 (PCSK9), is a PCSK9 inhibitor produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture. Alirocumab biosimilar consists of two disulfide-linked human heavy chains, each covalently linked through a disulfide bond to a human kappa light chain. A single Nlinked glycosylation site is located in each heavy chain within the CH2 domain of the Fc constant region of the molecule. The variable domains of the heavy and light chains combine to form the PCSK9 binding site within the antibody. Alirocumab biosimilar has an approximate molecular weight of 146 kDa.

Additional Text

Uniprot ID

Q8NBP7

Gene Name

PCSK9

Gene ID

255738

Purification

Protein A/G Purified

Concentration

1-5 mg/ml

Antibody Clonality

Recombinant Monoclonal

Storage Note

Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

ICH4016 Datasheet

Price

£899.00

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