Utomilumab Biosimilar - Research Grade
Catalogue Number: ICH5014-ICB
| Manufacturer: | IchorBio |
| Type: | Recombinant Monoclonal |
| Alias: | 4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 mg, 20 mg, 5 mg, 50 mg, 1 mg, 100 mg |
| Host name: | |
| Clone: | |
| Isotype: | IgG2, lambda |
| Immunogen: | |
| Application: | FA |
Description
Description: RUO Utomilumab is a fully-human IgG2 agonist mAb that selectively binds human 4-1BB/CD137, resulting in NF-κB activation and downstream cytokine production in cell lines and primary lymphocytes. Utomilumab can induce human leukocyte proliferation and has demonstrated significant antitumor activity as a single agent in human peripheral blood lymphocyte (PBL) SCID xenograft tumor models.
Additional Text
Gene ID
3604
Gene Name
TNFRSF9
Concentration
5 mg/ml
Uniprot ID
Q07011
Purification
Protein A/G Purified
Antibody Clonality
Recombinant Monoclonal
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Storage Note
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
ICH5014 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations