Atibuclimab Biosimilar - Research Grade

Catalogue Number: ICH5016-ICB

Manufacturer:	IchorBio
Type:	Recombinant Monoclonal
Shipping Condition:	Blue Ice
Unit(s):	10 mg, 20 mg, 5 mg, 50 mg, 1 mg, 100 mg
Host name:
Clone:
Isotype:	IgG4
Immunogen:
Application:	FA

Overview
Datasheets

Description

Description: RUO atibuclimab is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. It acts as a pattern recognition receptor for bacterial cell wall components in gram-positive and negative bacteria. CD14 antibody action stimulates a pro-inflammatory cytokine cascade often associated with inflammation in sepsis. Atibuclimab neutralization of this antibody results in the inhibition of TNF-a, IL-6 and IL-10, dampening systemic inflammatory responses. Atibuclimab also delays the release of sTNFR(1) and IL-1ra.

Additional Text

Gene Name

CD14

Concentration

5 mg/ml

Gene ID

929

Purification

Protein A/G Purified

Uniprot ID

P08571

Antibody Clonality

Recombinant Monoclonal

Application Notes

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Storage Note

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

ICH5016 Datasheet

Price

£899.00

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Quantity
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