Theralizumab Biosimilar - Research Grade
Catalogue Number: ICH5023-ICB
| Manufacturer: | IchorBio |
| Type: | Recombinant Monoclonal |
| Alias: | TGN1412, CD28-SuperMAB, TAB08 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 mg, 10 mg, 20 mg, 50 mg, 1 mg, 100 mg |
| Host name: | |
| Clone: | |
| Isotype: | IgG4 |
| Immunogen: | |
| Application: | FA |
Description
Description: Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system's T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
Additional Text
Gene ID
940
Concentration
5 mg/ml
Gene Name
CD28
Uniprot ID
P10747
Purification
Protein A/G Purified
Antibody Clonality
Recombinant Monoclonal
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Storage Note
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
ICH5023 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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