SSP-SAP
Catalogue Number: IT-11-ATS
| Manufacturer: | Advanced Targeting Systems |
| Preservative: | No preservative |
| Type: | Targeted Toxin |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
Description
Description: This targeted toxin (molecular weight 33 kDa) recognizes substance P receptor-bearing neurons in vivo. SSPSAP is a chemical conjugate of the peptidase-resistant [Sar9 , Met(O2 ) 11] analog of Substance P and the ribosome-inactivating protein, saporin (Cat. #PR-01). This product is routinely tested by cytotoxicity assay.
Additional Text
Usage Information
SSP-SAP eliminates cells expressing the Substance P (NK-1) receptor. All other cells are left untouched, even when they are the predominant cell type. This specific analog of SP-saporin resists peptidase digestion, allowing a greater diffusion from the injection site before its metabolism. Not suitable for retrograde transport.
Short Description
a tool for eliminating cells that express substance P receptor (NK-1); targeted via Substance P, eliminated via saporin
IT-11 Datasheet
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