Catalogue Number: IT-23-ATS
Manufacturer: | Advanced Targeting Systems |
Preservative: | No preservative |
Type: | Targeted Toxin |
Shipping Condition: | RT |
Unit(s): | 100 ug, 25 ug, 250 ug |
Host name: | Mouse |
Clone: | |
Isotype: | |
Immunogen: |
Description: This targeted toxin recognizes cells that express SERT. The sequence of the peptide antigen is identical in rat, mouse, human, and other mammalian species. Anti-SERT-SAP is a chemical conjugate of a monoclonal antibody to the fourth extracellular domain of serotonin re-uptake transporter (SERT, Cat. #AB-N40) and the ribosome-inactivating protein, saporin (Cat. #PR-01). This product is routinely tested by cytotoxicity assay.
Anti-SERT-SAP specifically eliminates SERT-expressing cells in vitro and in vivo. All other cells are left untouched.
a tool for eliminating cells that express serotonin re-uptake transporter; targeted via a monoclonal antibody to the fourth extracellular domain of SERT, eliminated via saporin