Catalogue Number: IT-25-ATS
Manufacturer: | Advanced Targeting Systems |
Preservative: | No preservative |
Type: | Targeted Toxin |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 25 ug, 250 ug |
Host name: | Rat |
Clone: | |
Isotype: | |
Immunogen: |
Description: This targeted toxin recognizes cells that express DAT in rat and human. The toxin is a chemical conjugate of a rat monoclonal antibody to the second extracellular loop of the dopamine transporter (DAT-ECD, Cat. #ABN17) and the ribosome-inactivating protein, saporin (Cat. #PR-01).
Anti-DAT-SAP is highly specific for cells that express DAT, including mesencephalic dopamine neurons of the substantia nigra, pars compacta, and ventral tegmental area.
Monoclonal
a tool for eliminating cells that express dopamine transporter (DAT-ECD) in rat or human; targeted via a monoclonal antibody to the second extracellular loop of DAT, eliminated via saporin