FGF-SAP
Catalogue Number: IT-38-ATS
| Manufacturer: | Advanced Targeting Systems |
| Preservative: | No preservative |
| Type: | Targeted Toxin |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 25 ug, 250 ug |
Description
Description: This targeted toxin (average molecular weight 63 kDa) recognizes FGF receptor-expressing cells including neuronal cell types, cancer cells, and lens epithelial cells with cross reactivity in several mammalian species. FGF-2 has been well characterized demonstrating binding to all four of the FGF high-affinity tyrosine kinase transmembrane receptors including binding to FGF receptor-5 with lower affinity. FGF-SAP is a chemical conjugate of rat FGF-2, or basic fibroblast growth factor, and the ribosome-inactivating protein, saporin (Cat. #PR-01). This product is routinely tested by cytotoxicity assay.
Additional Text
Usage Information
FGF-SAP specifically eliminates cells expressing the FGF receptor. All other cells are left untouched.
Short Description
a tool for eliminating cells that express FGF receptor; targeted via rat FGF-2, or basic fibroblast growth factor, eliminated via saporin
IT-38 Datasheet
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