Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-HM1AB)
Catalogue Number: ITG-HM1AB-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 126.6 kDa(ITGA2)&83.2 kDa(ITGB1). Due to glycosylation, the protein migrates to 110-140 kDa based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | CD49b|GPIa-IIa|Integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; VLA-2 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | WB |
Description
Description: The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis.
Additional Text
Protein Tag
HIS Tag
Short Description
Recombinant Human Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr30-T1132(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Uniprot ID
P05556-1, P17301-1
ITG-HM1AB Datasheet
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