Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-HM2V3)
Catalogue Number: ITG-HM2V3-KAT
ITG-HM2V3 Image
ITG-HM2V3 Image
ITG-HM2V3 Image
ITG-HM2V3 Image
Immobilized Human ITGAV&ITGB3, hFc Tag at 1µg/ml (100µl/well) on the plate. Dose response curve for Biotinylated Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA.
ITG-HM2V3 Image
The purity of Human ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.
ITG-HM2V3 Image
Human ITGAV&ITGB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 131.90 kDa (ITGAV)&101.79 kDa (ITGB3). Due to glycosylation, the protein migrates to 140-160 kDa (ITGAV)&105-130 kDa (ITGB3) based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
Description
Description: ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
Additional Text
Protein Tag
hFC Tag
Short Description
Recombinant Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Val992(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Uniprot ID
P05106-1, P06756-1
ITG-HM2V3 Datasheet
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