Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein (ITG-HM4V8B)

Catalogue Number: ITG-HM4V8B-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 114 kDa (ITGAV)&76 kDa (ITGB8) kDa. Due to glycosylation, the protein migrates to 85-145 kDa based on Tris-Bis PAGE result.
Physical state:	Lyophilized
Type:	Fusion Protein
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug

Overview
Datasheets

Description

Description: Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation.

Additional Text

Protein Tag

HIS-AviTag™

Short Description

Recombinant Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

UniProt ID

P06756-1

ITG-HM4V8B Datasheet

ITG-HM4V8B MSDS

Price

£429.00

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