Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein (ITG-MM1V8)
Catalogue Number: ITG-MM1V8-KAT
ITG-MM1V8 Image
ITG-MM1V8 Image
ITG-MM1V8 Image
ITG-MM1V8 Image
The purity of Mouse ITGAV&ITGB8 is greater than 95% as determined by SEC-HPLC.
ITG-MM1V8 Image
Mouse ITGAV&ITGB8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
ITG-MM1V8 Image
Immobilized Mouse ITGAV&ITGB8, His Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 0.97µg/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 24 months |
| Molecular Weight: | The protein has a predicted MW of 111.6(ITGAV)&76.6(ITGB8) kDa. Due to glycosylation, the protein migrates to 80-140 kDa based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | Integrin alpha V beta 8; ITGAV&ITGB8 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation.
Additional Text
Protein Tag
HIS Tag
Gene Name
ITGAV, ITGB8
Short Description
Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail&Gly22-Ser679(ITGB8) basic tail.
Uniprot ID
P43406, Q0VBD0
Gene ID
16410; 320910
Storage Note
-20 to -80°C for 24 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
ITG-MM1V8 Datasheet
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