Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM2V3)
Catalogue Number: ITG-MM2V3-KAT
ITG-MM2V3 Image
ITG-MM2V3 Image
ITG-MM2V3 Image
ITG-MM2V3 Image
Mouse ITGAV&ITGB3, hFc Tag captured on CM5 Chip via Protein A can bind Human Vitronectin, His Tag with an affinity constant of 3.37 nM as determined in SPR assay (Biacore T200).
ITG-MM2V3 Image
The purity of Mouse ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.
ITG-MM2V3 Image
Mouse ITGAV&ITGB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 131.48 kDa(ITGAV)&101.58 kDa(ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 110-135 kDa and 50-60 kDa based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | WB |
Description
Description: ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
Additional Text
Protein Tag
hFC Tag
Gene Name
ITGAV, ITGB3
Short Description
Recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Uniprot ID
O54890, P43406
Gene ID
16410; 16416
ITG-MM2V3 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations