Catalogue Number: ITG-RM1V8-KAT
Manufacturer: | Kactus |
Shelf Life: | 24 months |
Molecular Weight: | The protein has a predicted MW of 112.1 kDa (ITGAV) and 75.3 kDa (ITGB8). Due to glycosylation, the protein migrates to 90-140 kDa based on Bis-Tris PAGE result. |
Physical state: | Lyophilized |
Type: | Fusion Protein |
Alias: | αVβ8; Integrin alpha V beta 8;ITGAV&ITGB8;Integrin alpha V β 8 |
Host Cell: | HEK293 cells |
Shipping Condition: | RT |
Unit(s): | 100 ug, 500 ug |
Application: | ELISA, WB |
Description: Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation.
HIS Tag
F6QSK2, F7F3K9
Recombinant Rhesus macaque Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe31-Pro993 (ITGAV) acidic tail and Glu43-Ser681 (ITGB8) basic tail.
-20 to -80°C for 24 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.