Catalogue Number: KET6013-ABK
Manufacturer: | Abbkine |
Type: | Human ELISA Kit |
Alias: | Interleukin 1β; IL1B; IL-1; IL1-BETA; IL1F2; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta |
Shipping Condition: | Blue Ice |
Unit(s): | 48 T, 96 T |
Range: | |
Sensitivity: | |
Sample type: | Cell Culture Supernatant, Other Biological Fluid, Plasma, Serum |
Sample size: | |
Application: | ELISA, sELISA |
Description: Interleukin 1β encoded by IL-1β gene is a member of the interleukin 1 cytokine family. Interleukin 1β is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). Interleukin 1β is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by Interleukin 1β in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. IL-1β gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
IL1B
3553
P01584
Colorimetric
EliKine™ Human IL-1β ELISA Kit employs a two-site sandwich ELISA to quantitate Human IL-1β.