Caspase-2 Assay Kit (Colorimetric)

Catalogue Number: KTA3021-ABK

Manufacturer:	Abbkine
Shelf Life:	12 months
Type:	Enzyme Assays
Shipping Condition:	Blue Ice
Unit(s):	100 T, 20 T, 50 T

Overview
Datasheets

Description

Description: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Mammalian caspases can be subdivided into three functional groups: initiator caspases (Caspase 2, 8, 9 and 10), executioner caspases (Caspase-3, 6 and 7), and inflammatory caspases (Caspase 1, 4, 5, 11 and 12). Caspase 2 belongs to a family of cysteine proteases that cleave proteins only at an amino acid following an aspartic acid residue. Within this family, caspase 2 is part of the Ich-1 subfamily, one of the most conserved caspases in different species of animal. It has a similar amino acid sequence to initiator caspases, including caspase 1, caspase 4, caspase 5, and caspase 9. It is produced as a zymogen, which contains a long pro-domain that is similar to that of caspase 9 and contains a protein interaction domain known as a CARD domain. Pro-caspase-2 contains two subunits, p19 and p12.

Additional Text

Short Description

Caspase-2 Assay Kit (Colorimetric) provides a simple and convenient method for detecting the activity of caspase-2.

KTA3021 Datasheet

Price

£241.00

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