Caspase-6 Assay Kit (Colorimetric)

Catalogue Number: KTA3024-ABK

Manufacturer:	Abbkine
Shelf Life:	12 months
Type:	Enzyme Assays
Shipping Condition:	Blue Ice
Unit(s):	100 T, 20 T, 50 T

Overview
Datasheets

Description

Description: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Mammalian caspases can be subdivided into three functional groups: initiator caspases (Caspase 2, 8, 9 and 10), executioner caspases (Caspase-3, 6 and 7), and inflammatory caspases (Caspase 1, 4, 5, 11 and 12). Caspase-6 (also known as Mch2) is a member of the caspase-family of cysteine proteases. During apoptosis procaspase-6 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-6 consists of large (18 kDa) and small (11 kDa) subunits which associate to form the active enzyme. Active caspase-6 has been shown involving in the proteolysis of PARP (poly ADP-ribose polymerase), an enzyme that is involved in DNA repair and genomic maintenance.

Additional Text

Short Description

Caspase-6 Assay Kit (Colorimetric) provides a simple and convenient method for detecting the activity of caspase-6.

KTA3024 Datasheet

Price

£241.00

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