Catalogue Number: LB4-HM4D4B-KAT
Manufacturer: | Kactus |
Shelf Life: | 12 months |
Molecular Weight: | The protein has a predicted MW of 14.77 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Tris-Bis PAGE result. |
Physical state: | Liquid |
Type: | Fusion Protein |
Host Cell: | HEK293 cells |
Shipping Condition: | Dry Ice |
Unit(s): | 100 ug, 500 ug |
Application: | WB |
Description: LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
HIS-AviTag™
AAH26309.1
Recombinant Biotinylated Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Lys123.
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.