Catalogue Number: LIL-CM1B4-KAT
Manufacturer: | Kactus |
Shelf Life: | 12 months |
Molecular Weight: | The protein has a predicted MW of 27.2 kDa. Due to glycosylation, the protein migrates to 35-42 kDa based on Tris-Bis PAGE result. |
Physical state: | Lyophilized |
Type: | Fusion Protein |
Alias: | HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K |
Host Cell: | HEK293 cells |
Shipping Condition: | RT |
Unit(s): | 100 ug, 500 ug |
Application: | ELISA, WB |
Description: LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
HIS Tag
XP_015297198.1
Recombinant Cynomolgus LILRB4/CD85k/ILT3 Protein Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Glu259.
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.