Human LILRB1/CD85j/ILT2 Protein (LIL-HM2B1)
Catalogue Number: LIL-HM2B1-KAT
LIL-HM2B1 Image
LIL-HM2B1 Image
LIL-HM2B1 Image
LIL-HM2B1 Image
LIL-HM2B1 Image
Human LILRB1, hFc Tag captured on Protein A Chip can bind Human HLA-G Tetramer, His Tag with an affinity constant of 1.49nM as determined in SPR assay (Biacore T200).
LIL-HM2B1 Image
The purity of Human LILRB1 is greater than 95% as determined by SEC-HPLC.
LIL-HM2B1 Image
Human LILRB1 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
LIL-HM2B1 Image
Immobilized Human LILRB1, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Anti-LILRB1 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 73.8 kDa. Due to glycosylation, the protein migrates to 78-105 kDa based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | ILT2; ILT-2; ILT2FLJ37515; LILRB1; LIR1; MIR7; CD85J; XXbac-BCX85G21.4 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.
Additional Text
Protein Tag
hFC Tag
Short Description
Recombinant Human LILRB1/CD85j/ILT2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly24-Arg457.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
UniProt ID
Q8NHL6-1
LIL-HM2B1 Datasheet
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