Biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3B)

Catalogue Number: LIL-HM4A3B-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 47.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Physical state:Lyophilized
Type:Fusion Protein
Alias:CD85e; HM31; HM43; ILT6; ILT-6; LILRA3; LIR4; LIR-4HM43e3
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: WB

Description

Description: Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31, is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains. Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

Additional Text

Gene ID

11026

Uniprot ID

Q8N6C8

Gene Name

LILRA3

Protein Tag

HIS-AviTag™

Short Description

Recombinant Biotinylated Human LILRA3/CD85e Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly24-Glu439.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Price
£375.00


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