Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein (MHC-HM408B)
Catalogue Number: MHC-HM408B-KAT
MHC-HM408B Image
MHC-HM408B Image
MHC-HM408B Image
The purity of Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer is greater than 95% as determined by SEC-HPLC.
MHC-HM408B Image
Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | WB |
Description
Description: Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Additional Text
Gene Name
B2M
Gene ID
567
Protein Tag
HIS-AviTag™
Short Description
Recombinant Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and PLFQVPEPV peptide.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Uniprot ID
A0A140T913, P61769
MHC-HM408B Datasheet
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