PE-Labeled Human HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein (MHC-HM418TP)
Catalogue Number: MHC-HM418TP-KAT
MHC-HM418TP Image
MHC-HM418TP Image
Immobilized PE-Labeled Human HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer, His Tag at 5µg/ml (100µl/well) on the plate. Dose response curve for Anti-HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Antibody, hFc Tag with the EC50 of 1.67µg/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
Description
Description: Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Additional Text
Gene Name
B2M
Uniprot ID
P61769
Accession Number
NP_002107.3
Protein Tag
HIS-AviTag™
Short Description
Recombinant PE-Labeled Human HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human KRAS G12V (HLA-A*03:01) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and VVVGAVGVGK peptide.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
MHC-HM418TP Datasheet
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