Catalogue Number: MHC-HM432B-KAT
Manufacturer: | Kactus |
Shelf Life: | 12 months |
Molecular Weight: | The protein has a predicted MW of 50.70 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result. |
Physical state: | Lyophilized |
Type: | Fusion Protein |
Host Cell: | HEK293 cells |
Shipping Condition: | RT |
Unit(s): | 100 ug, 500 ug |
Application: | WB |
Description: Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
B2M
567
P61769
HIS-AviTag™
AAA03604.1
Recombinant Biotinylated Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus..It contains Gly25-Thr305(HLA-A*02:03),Ile21-Met119(B2M) and FMNKFIYEI peptide.
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.