Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T)

Catalogue Number: MHC-HM432T-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
Physical state:	Lyophilized
Type:	Fusion Protein
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	WB

Overview
Datasheets

Description

Description: Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.

Additional Text

Gene Name

B2M

Gene ID

567

Uniprot ID

P61769

Protein Tag

HIS-AviTag™

Accession Number

AAA03604.1

Short Description

Recombinant Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein is expressed from HEK293 His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*02:03),Ile21-Met119(B2M) and FMNKFIYEI peptide.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

MHC-HM432T Datasheet

MHC-HM432T MSDS

Price

£536.00

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