Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein (MHC-HM439)
Catalogue Number: MHC-HM439-KAT
MHC-HM439 Image
MHC-HM439 Image
MHC-HM439 Image
The purity of Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer is greater than 95% as determined by SEC-HPLC.
MHC-HM439 Image
Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
Description
Description: Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Additional Text
Gene Name
B2M
Uniprot ID
P61769
Protein Tag
HIS-AviTag™
Accession Number
AAV53343.1
Short Description
Recombinant Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGACGVGK peptide.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
MHC-HM439 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations